| Reaction Details |
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 | Report a problem with these data |
| Target | Equilibrative nucleoside transporter 1 |
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| Ligand | BDBM50118812 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_181683 (CHEMBL786457) |
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| Ki | 28200±n/a nM |
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| Citation |  Kim, HO; Ji, XD; Siddiqi, SM; Olah, ME; Stiles, GL; Jacobson, KA 2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors. J Med Chem37:3614-21 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Equilibrative nucleoside transporter 1 |
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| Name: | Equilibrative nucleoside transporter 1 |
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| Synonyms: | Ent1 | S29A1_RAT | Slc29a1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50023.68 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_181682 |
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| Residue: | 457 |
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| Sequence: | MTTSHQPQDRYKAVWLIFFVLGLGTLLPWNFFITATQYFTSRLNTSQNISLVTNQSCEST
EALADPSVSLPARSSLSAIFNNVMTLCAMLPLLIFTCLNSFLHQKVSQSLRILGSLLAIL
LVFLVTATLVKVQMDALSFFIITMIKIVLINSFGAILQASLFGLAGVLPANYTAPIMSGQ
GLAGFFTSVAMICAVASGSKLSESAFGYFITACAVVILAILCYLALPWMEFYRHYLQLNL
AGPAEQETKLDLISEGEEPRGGREESGVPGPNSLPANRNQSIKAILKSIWVLALSVCFIF
TVTIGLFPAVTAEVESSIAGTSPWKNCYFIPVACFLNFNVFDWLGRSLTAICMWPGQDSR
WLPVLVACRVVFIPLLMLCNVKQHHYLPSLFKHDVWFITFMAAFAFSNGYLASLCMCFGP
KKVKPAEAETAGNIMSFFLCLGLALGAVLSFLLRALV
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| BDBM50118812 |
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| n/a |
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| Name | BDBM50118812 |
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| Synonyms: | (2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide | (2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-N-methyltetrahydrofuran-2-carboxamide | (2S,3S,4R,5R)-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyl-tetrahydrofuran-2-carboxamide | (3R,4S,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide | (3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide | (N-6-(3-iodobenzyl)adenosine-5'-N-methyluronamide | 3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide | CHEMBL119709 | IB-MECA | N6-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19IN6O4 |
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| Mol. Mass. | 510.2857 |
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| SMILES | CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3cccc(I)c3)ncnc12 |r| |
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| Structure | 
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