| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM50005836 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2242 (CHEMBL617187) |
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| Ki | 7.2±n/a nM |
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| Citation |  Buchheit, KH; Gamse, R; Giger, R; Hoyer, D; Klein, F; Klöppner, E; Pfannkuche, HJ; Mattes, H The serotonin 5-HT4 receptor. 1. Design of a new class of agonists and receptor map of the agonist recognition site. J Med Chem38:2326-30 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT2A | 5HT2A_BOVIN | 5HTR2A | HTR2A | Serotonin 2a (5-HT2a) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52578.24 |
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| Organism: | BOVINE |
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| Description: | 5-HT2A HTR2A BOVINE::Q75Z89 |
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| Residue: | 470 |
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| Sequence: | MDILCEENTSLSSTTNSLMQLHADTRLYSTDFNSGEGNTSNAFNWTVDSENRTNLSCEGC
LSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSTLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADENFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDPGTRTKLASFSFLPQSSLSSEKLFQRSIH
REPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNRDVIEAL
LNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKS
SQLQMGPKKNSKKDDKTTDNDCTMVALGKEHPEDAPADSSNTVNEKVSCV
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| BDBM50005836 |
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| n/a |
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| Name | BDBM50005836 |
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| Synonyms: | 4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide | 4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide | CHEMBL560739 | CISAPRIDE | PROPULSID | US10167299, Cisapride | US10800776, Example Cisapride | US9221790, Cisapride | cid_5311047 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H29ClFN3O4 |
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| Mol. Mass. | 465.945 |
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| SMILES | COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC |
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| Structure | 
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