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Target5-hydroxytryptamine receptor 1D
LigandBDBM50033434
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2009 (CHEMBL617304)
Ki 0.92±n/a nM
Citation Perez, MFourrier, CSigogneau, IPauwels, PJPalmier, CJohn, GWValentin, JPHalazy, S Synthesis and serotonergic activity of arylpiperazide derivatives of serotonin: potent agonists for 5-HT1D receptors. J Med Chem38:3602-7 (1995) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1D
Name:5-hydroxytryptamine receptor 1D
Synonyms:5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:41920.63
Organism:Homo sapiens (Human)
Description:Receptor binding assays were performed using human clone stably expressed in CHO cells.
Residue:377
Sequence:
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
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  Blast E-value cutoff:
BDBM50033434
n/a
NameBDBM50033434
Synonyms:2-(4-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-acetyl}-piperazin-1-yl)-benzonitrile | CHEMBL119927
TypeSmall organic molecule
Emp. Form.C23H25N5O2
Mol. Mass.403.4769
SMILESNCCc1c[nH]c2ccc(OCC(=O)N3CCN(CC3)c3ccccc3C#N)cc12
Structure
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