| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine deaminase |
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| Ligand | BDBM50023668 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_30794 (CHEMBL645070) |
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| Ki | 380±n/a nM |
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| Citation |  Cristalli, G; Vittori, S; Eleuteri, A; Volpini, R; Camaioni, E; Lupidi, G; Mahmood, N; Bevilacqua, F; Palù, G Synthesis and biological evaluation of N6-cycloalkyl derivatives of 1-deazaadenine nucleosides: a new class of anti-human immunodeficiency virus agents. J Med Chem38:4019-25 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Adenosine deaminase |
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| Name: | Adenosine deaminase |
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| Synonyms: | ADA | ADA_BOVIN | Adenosine aminohydrolase |
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| Type: | Enzyme |
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| Mol. Mass.: | 40910.44 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 363 |
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| Sequence: | MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
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|
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| BDBM50023668 |
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| n/a |
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| Name | BDBM50023668 |
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| Synonyms: | 2-(7-Amino-imidazo[4,5-b]pyridin-3-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol | CHEMBL17351 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H14N4O4 |
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| Mol. Mass. | 266.2533 |
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| SMILES | Nc1ccnc2n(cnc12)C1O[C@H](CO)[C@@H](O)[C@H]1O |
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| Structure | 
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