| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM50004327 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2613 (CHEMBL617481) |
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| Ki | 2.5±n/a nM |
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| Citation |  Ismaiel, AM; Arruda, K; Teitler, M; Glennon, RA Ketanserin analogues: the effect of structural modification on 5-HT2 serotonin receptor binding. J Med Chem38:1196-202 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52852.05 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Rat cortex membranes 5-HT2A receptors. |
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| Residue: | 471 |
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| Sequence: | MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYK
SSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
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| BDBM50004327 |
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| n/a |
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| Name | BDBM50004327 |
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| Synonyms: | (1-Phenethyl-piperidin-4-yl)-phenyl-methanol | CHEMBL18972 | Glemanserin | MDL 11,939 | MDL-11939 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H25NO |
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| Mol. Mass. | 295.4186 |
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| SMILES | OC(C1CCN(CCc2ccccc2)CC1)c1ccccc1 |
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| Structure | 
|
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