Ki Summary

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Target

P-selectin

Ligand

BDBM50450369

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_200030 (CHEMBL810719)

IC50

>1000000±n/a nM

Citation

Wada, Y; Saito, T; Matsuda, N; Ohmoto, H; Yoshino, K; Ohashi, M; Kondo, H; Ishida, H; Kiso, M; Hasegawa, A Studies on selectin blockers. 2. Novel selectin blocker as potential therapeutics for inflammatory disorders. J Med Chem39:2055-9 (1996) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

P-selectin

Name:

P-selectin

Synonyms:

Type:

PROTEIN

Mol. Mass.:

90834.61

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1438999

Residue:

830

Sequence:

MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
PEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRV
RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
SCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGLQCPALTTPGQGTMYCRHHPG
TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVA
STIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP

BDBM50450369

n/a

Name

BDBM50450369

Synonyms:

SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLex | sialyl LewisX

Type

Small organic molecule

Emp. Form.

C31H52N2O23

Mol. Mass.

820.7442

SMILES

[H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(O[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]([C@H](O)CO)[C@H](O[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)[C@@H](NC(C)=O)C=O)[C@@H]1O)C(O)=O)[C@H](O)[C@H](O)CO

Structure