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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Reverse transcriptase/RNaseH | ||
| Ligand | BDBM50050814 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_195535 (CHEMBL800982) | ||
| IC50 | 5±n/a nM | ||
| Citation |  Silverman, BD; Platt, DE Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition. J Med Chem39:2129-40 (1996) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Reverse transcriptase/RNaseH | |||
| Name: | Reverse transcriptase/RNaseH | ||
| Synonyms: | HIV-1 Reverse Transcriptase RNase H | Human immunodeficiency virus type 1 reverse transcriptase | Reverse transcriptase/RNaseH | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 65229.15 | ||
| Organism: | Human immunodeficiency virus 1 | ||
| Description: | ChEMBL_1473730 | ||
| Residue: | 566 | ||
| Sequence: |
| ||
| BDBM50050814 | |||
| n/a | |||
| Name | BDBM50050814 | ||
| Synonyms: | 5-Chloro-8-methyl-7-(3-methyl-but-2-enyl)-6,7,8,9-tetrahydro-2H-2,7,9a-triaza-benzo[cd]azulene-1-thione | CHEMBL306904 | tivirapine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H20ClN3S | ||
| Mol. Mass. | 321.868 | ||
| SMILES | CC1Cn2c3c(CN1CC=C(C)C)c(Cl)ccc3[nH]c2=S |(13.69,-4.97,;12.16,-5,;11.48,-3.62,;9.99,-3.27,;8.8,-4.23,;8.8,-5.78,;9.99,-6.74,;11.48,-6.4,;12.44,-7.62,;11.87,-9.05,;12.82,-10.26,;12.25,-11.69,;14.35,-10.03,;7.47,-6.55,;7.47,-8.09,;6.13,-5.78,;6.13,-4.23,;7.47,-3.46,;7.8,-1.96,;9.45,-1.84,;10.35,-.58,)| | ||
| Structure | 
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