| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A3 |
|---|
| Ligand | BDBM50035800 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_30485 (CHEMBL641437) |
|---|
| Ki | 6200±n/a nM |
|---|
| Citation |  van Rhee, AM; Jiang, JL; Melman, N; Olah, ME; Stiles, GL; Jacobson, KA Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors. J Med Chem39:2980-9 (1996) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A3 |
|---|
| Name: | Adenosine receptor A3 |
|---|
| Synonyms: | AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 36643.73 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_479910 |
|---|
| Residue: | 320 |
|---|
| Sequence: | MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALAD
IAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRY
RTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMV
FFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFL
FALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILR
ACRLCQTSDSLDSNLEQTTE
|
|
|
|---|
| BDBM50035800 |
|---|
| n/a |
|---|
| Name | BDBM50035800 |
|---|
| Synonyms: | (S)-2,6-Dimethyl-5-nitro-4-(2-trifluoromethyl-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid methyl ester | CHEMBL105672 | CHEMBL283013 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H15F3N2O4 |
|---|
| Mol. Mass. | 356.2965 |
|---|
| SMILES | COC(=[OH+])C1=C(C)[N-]C(C)=C(C1c1ccccc1C(F)(F)F)[N+]([O-])=O |c:4,9| |
|---|
| Structure | 
|
|---|
Search and Browse
