| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase |
|---|
| Ligand | BDBM50053181 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_40245 (CHEMBL654925) |
|---|
| IC50 | 2900±n/a nM |
|---|
| Citation |  Richter, HG; Angehrn, P; Hubschwerlen, C; Kania, M; Page, MG; Specklin, JL; Winkler, FK Design, synthesis, and evaluation of 2 beta-alkenyl penam sulfone acids as inhibitors of beta-lactamases. J Med Chem39:3712-22 (1996) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-lactamase |
|---|
| Name: | Beta-lactamase |
|---|
| Synonyms: | BLAC_BACLI | blaP | penP |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 33993.80 |
|---|
| Organism: | Bacillus licheniformis |
|---|
| Description: | ChEMBL_571690 |
|---|
| Residue: | 307 |
|---|
| Sequence: | MKLWFSTLKLKKAAAVLLFSCVALAGCANNQTNASQPAEKNEKTEMKDDFAKLEEQFDAK
LGIFALDTGTNRTVAYRPDERFAFASTIKALTVGVLLQQKSIEDLNQRITYTRDDLVNYN
PITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGPESLKKELRKIGDEVTNPERFE
PELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRELLIDWMKRNTTGDALIRAGVP
DGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSRDKKDAKYDDKLIAEATKVVMK
ALNMNGK
|
|
|
|---|
| BDBM50053181 |
|---|
| n/a |
|---|
| Name | BDBM50053181 |
|---|
| Synonyms: | (2S,3S,5R)-3-((Z)-2-Ethoxycarbonyl-vinyl)-3-methyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | CHEMBL122209 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H15NO7S |
|---|
| Mol. Mass. | 317.315 |
|---|
| SMILES | CCOC(=O)\C=C/[C@@]1(C)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
