Ki Summary

Reaction Details

Report a problem with these data

Target

Muscarinic receptor M1

Ligand

BDBM50055976

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_140161 (CHEMBL745466)

0.01±n/a nM

Citation

Visser, TJ; van Waarde, A; Jansen, TJ; Visser, GM; van der Mark, TW; Kraan, J; Ensing, K; Vaalburg, W Stereoselective synthesis and biodistribution of potent [11C]-labeled antagonists for positron emission tomography imaging of muscarinic receptors in the airways. J Med Chem40:117-24 (1997) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Muscarinic receptor M1

Name:

Muscarinic receptor M1

Synonyms:

Muscarinic acetylcholine receptor M1

Type:

PROTEIN

Mol. Mass.:

15022.43

Organism:

Bos taurus

Description:

ChEMBL_140161

Residue:

139

Sequence:

ETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRTPRLLQAYS
WKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPAKQPPRSSPNTVKRPTRKG
RERAGKGQKPRGKEQLAKR

BDBM50055976

n/a

Name

BDBM50055976

Synonyms:

(R)-3-((R)-2-Cyclohexyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-azonia-bicyclo[2.2.2]octane; iodide | CHEMBL21812

Type

Small organic molecule

Emp. Form.

C22H32NO3

Mol. Mass.

358.4938

SMILES

C[N+]12CCC(CC1)[C@H](C2)OC(=O)[C@@](O)(C1CCCCC1)c1ccccc1 |wU:12.14,wD:12.13,7.10,TLB:9:7:2.3:6.5,(13.94,-4.53,;13.94,-2.99,;14.71,-1.66,;13.24,-1.26,;14.01,.06,;15.34,-.72,;15.34,-2.26,;12.68,-.71,;12.68,-2.25,;11.35,.06,;10.02,-.71,;10.02,-2.26,;8.66,.09,;9.46,1.42,;7.33,.86,;6,.09,;4.67,.86,;4.67,2.4,;6,3.17,;7.33,2.4,;7.89,-1.27,;6.35,-1.27,;5.58,-2.6,;6.35,-3.94,;7.89,-3.95,;8.66,-2.62,)|

Structure