| Reaction Details |
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 | Report a problem with these data |
| Target | Antithrombin-III |
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| Ligand | BDBM50369253 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_35868 (CHEMBL652036) |
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| Kd | 7±n/a nM |
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| Citation |  Petitou, M; Duchaussoy, P; Jaurand, G; Gourvenec, F; Lederman, I; Strassel, JM; Bârzu, T; Crépon, B; Hérault, JP; Lormeau, JC; Bernat, A; Herbert, JM Synthesis and pharmacological properties of a close analogue of an antithrombotic pentasaccharide (SR 90107A/ORG 31540). J Med Chem40:1600-7 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Antithrombin-III |
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| Name: | Antithrombin-III |
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| Synonyms: | ANT3_HUMAN | AT3 | ATIII | Antithrombin-III | Antithrombin-III precursor | Coagulation factor X/antithrombin III | SERPINC1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52602.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_35871 |
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| Residue: | 464 |
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| Sequence: | MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEK
KATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFA
MTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFG
DKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAIN
ELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQ
VLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDG
FSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAV
VIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
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| BDBM50369253 |
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| n/a |
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| Name | BDBM50369253 |
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| Synonyms: | CHEMBL1909451 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H54N2O50S8 |
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| Mol. Mass. | 1583.334 |
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| SMILES | CO[C@@H]1O[C@H](COS([O-])(=O)=O)[C@@H](O[C@H]2O[C@H]([C@H](O[C@@H]3O[C@H](COS([O-])(=O)=O)[C@@H](O[C@H]4O[C@@H]([C@@H](O[C@@H]5O[C@@H](COS([O-])(=O)=O)[C@H](OC)[C@@H](OC)[C@@H]5NS([O-])(=O)=O)[C@@H](OC)[C@@H]4OC)C([O-])=O)[C@@H](OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H](OC)[C@@H]2OS([O-])(=O)=O)C([O-])=O)[C@H](OC)[C@H]1NS([O-])(=O)=O |r,@:7,66,81,@@:23,39,51,72,93| |
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| Structure | 
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