| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50058154 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_145567 (CHEMBL749571) |
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| Ki | >3000±n/a nM |
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| Citation |  Ohkawa, S; DiGiacomo, B; Larson, DL; Takemori, AE; Portoghese, PS 7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors. J Med Chem40:1720-5 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | KOR-1 | MSL-1 | OPIATE Kappa | OPRK_MOUSE | Oprk1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42656.78 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P33534 |
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| Residue: | 380 |
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| Sequence: | MESPIQIFRGDPGPTCSPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLESAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRV
RNTVQDPASMRDVGGMNKPV
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| BDBM50058154 |
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| n/a |
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| Name | BDBM50058154 |
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| Synonyms: | 7-(4'-Methoxy-2'-spiroindanyl)naltrexone | CHEMBL297933 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H31NO5 |
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| Mol. Mass. | 473.5601 |
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| SMILES | COc1cccc2CC3(Cc12)C[C@@]1(O)C2Cc4ccc(O)c5OC(C3=O)C1(CCN2CC1CC1)c45 |TLB:30:29:12:34.16.15,21:34:12:29.27.28,13:12:34.16.15:29.27.28| |
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| Structure | 
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