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TargetMu-type opioid receptor
LigandBDBM50058150
Substrate/Competitorn/a
Meas. Tech.ChEMBL_148519
Ki 7.8±n/a nM
Citation Ohkawa SDiGiacomo BLarson DLTakemori AEPortoghese PS 7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors. J Med Chem 40:1720-5 (1997) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOR-1 | Mor | OPIATE Mu | Oprm | Oprm1
Type:Enzyme Catalytic Domain
Mol. Mass.:44431.62
Organism:MOUSE
Description:OPIATE Mu OPRM1 MOUSE::P42866
Residue:398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50058150
n/a
NameBDBM50058150
Synonyms:7-(5',6'-Benzo-2'-spiroindanyl)naltrexone | CHEMBL49704
TypeSmall organic molecule
Emp. Form.C32H31NO4
Mol. Mass.493.5928
SMILESOc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)C(=O)C1(Cc2cc4ccccc4cc2C1)C[C@@]35O |TLB:36:35:18.4.5:7.13.12,THB:8:7:35:18.4.5,17:18:35:7.13.12|
Structure
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