Reaction Details |
| Report a problem with these data |
Target | Mu-type opioid receptor |
---|
Ligand | BDBM50060072 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_147101 (CHEMBL758266) |
---|
IC50 | >10000±n/a nM |
---|
Citation | Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH Evolution of the Dmt-Tic pharmacophore: N-terminal methylated derivatives with extraordinary delta opioid antagonist activity. J Med Chem40:3100-8 (1997) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Mu-type opioid receptor |
---|
Name: | Mu-type opioid receptor |
Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 11165.58 |
Organism: | GUINEA PIG |
Description: | P97266 |
Residue: | 98 |
Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
|
|
|
BDBM50060072 |
---|
n/a |
---|
Name | BDBM50060072 |
Synonyms: | 2-[(R)-3-(4-Hydroxy-2,6-dimethyl-phenyl)-2-methylamino-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid | CHEMBL107754 |
Type | Small organic molecule |
Emp. Form. | C22H26N2O4 |
Mol. Mass. | 382.4528 |
SMILES | CN[C@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(O)=O |
Structure |
|