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TargetMu-type opioid receptor
LigandBDBM50061064
Substrate/Competitorn/a
Meas. Tech.ChEMBL_148398
Ki 14±n/a nM
Citation Dondio GRonzoni SEggleston DSArtico MPetrillo PPetrone GVisentin LFarina CVecchietti VClarke GD Discovery of a novel class of substituted pyrrolooctahydroisoquinolines as potent and selective delta opioid agonists, based on an extension of the message-address concept. J Med Chem 40:3192-8 (1997) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOR-1 | Mor | OPIATE Mu | Oprm | Oprm1
Type:Enzyme Catalytic Domain
Mol. Mass.:44431.62
Organism:MOUSE
Description:OPIATE Mu OPRM1 MOUSE::P42866
Residue:398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50061064
n/a
NameBDBM50061064
Synonyms:(4aR,8aS)-6-Cyclopropylmethyl-8a-(3-hydroxy-phenyl)-3-methyl-4,4a,5,6,7,8,8a,9-octahydro-1H-pyrrolo[2,3-g]isoquinoline-2-carboxylic acid diethylamide | CHEMBL324236
TypeSmall organic molecule
Emp. Form.C27H37N3O2
Mol. Mass.435.6016
SMILESCCN(CC)C(=O)c1[nH]c2C[C@]3(CCN(CC4CC4)C[C@@H]3Cc2c1C)c1cccc(O)c1
Structure
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