| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50060603 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_59491 (CHEMBL670143) |
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| Ki | 122±n/a nM |
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| Citation |  Baures, PW; Ojala, WH; Costain, WJ; Ott, MC; Pradhan, A; Gleason, WB; Mishra, RK; Johnson, RL Design, synthesis, and dopamine receptor modulating activity of diketopiperazine peptidomimetics of L-prolyl-L-leucylglycinamide. J Med Chem40:3594-600 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50698.79 |
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| Organism: | BOVINE |
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| Description: | P20288 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFLKILHC
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| BDBM50060603 |
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| n/a |
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| Name | BDBM50060603 |
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| Synonyms: | (3S,7aR)-6-((2R,8aS)-1,4-Dioxo-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl)-5-oxo-hexahydro-pyrrolo[2,1-b]thiazole-3-carboxylic acid amide |
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| Type | Small organic molecule |
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| Emp. Form. | C14H18N4O4S |
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| Mol. Mass. | 338.382 |
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| SMILES | NC(=O)[C@H]1CS[C@@H]2CC(N3CC(=O)N4CCC[C@H]4C3=O)C(=O)N12 |
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| Structure | 
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