| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
|---|
| Ligand | BDBM50368882 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_140182 (CHEMBL744099) |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  Ronsisvalle, G; Marrazzo, A; Prezzavento, O; Pasquinucci, L; Vittorio, F; Pittalà, V; Pappalardo, MS; Cacciaguerra, S; Spampinato, S (+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties. J Med Chem41:1574-80 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M2 |
|---|
| Name: | Muscarinic acetylcholine receptor M2 |
|---|
| Synonyms: | ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 51555.53 |
|---|
| Organism: | RAT |
|---|
| Description: | P10980 |
|---|
| Residue: | 466 |
|---|
| Sequence: | MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRI
VKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
|
|
|
|---|
| BDBM50368882 |
|---|
| n/a |
|---|
| Name | BDBM50368882 |
|---|
| Synonyms: | CHEMBL147585 | SK&F-10047 | SK-10047 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H21NO |
|---|
| Mol. Mass. | 243.344 |
|---|
| SMILES | CC1C2Cc3ccc(O)cc3C1CCN2CC=C |TLB:0:1:10.4.3:14.12.13,15:14:1:10.4.3,THB:9:10:1:14.12.13| |
|---|
| Structure | 
|
|---|
Search and Browse
