| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50162487 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29131 (CHEMBL637553) |
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| Ki | 254±n/a nM |
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| Citation |  Franchetti, P; Cappellacci, L; Marchetti, S; Trincavelli, L; Martini, C; Mazzoni, MR; Lucacchini, A; Grifantini, M 2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. J Med Chem41:1708-15 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36602.99 |
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| Organism: | BOVINE |
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| Description: | ADENOSINE 0 BOVINE::P28190 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPVDEDAPAERPDD
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| BDBM50162487 |
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| n/a |
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| Name | BDBM50162487 |
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| Synonyms: | 3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-4-methyl-tetrahydro-furan-2-carboxylic acid methylamide | CHEMBL194031 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21IN6O4 |
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| Mol. Mass. | 524.3123 |
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| SMILES | CNC(=O)[C@H]1O[C@@H](n2cnc3c(NCc4cccc(I)c4)ncnc23)[C@](C)(O)[C@@H]1O |
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| Structure | 
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