Ki Summary

Reaction Details

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Target

Somatostatin receptor type 3

Ligand

BDBM50064772

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_200506 (CHEMBL803851)

0.66±n/a nM

Citation

Yang, L; Guo, L; Pasternak, A; Mosley, R; Rohrer, S; Birzin, E; Foor, F; Cheng, K; Schaeffer, J; Patchett, AA Spiro[1H-indene-1,4'-piperidine] derivatives as potent and selective non-peptide human somatostatin receptor subtype 2 (sst2) agonists. J Med Chem41:2175-9 (1998) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Somatostatin receptor type 3

Name:

Somatostatin receptor type 3

Synonyms:

SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)

Type:

Protein

Mol. Mass.:

45855.97

Organism:

Homo sapiens (Human)

Description:

P32745

Residue:

418

Sequence:

MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL
GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM
AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV
FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV
WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA
LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE
SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL

BDBM50064772

n/a

Name

BDBM50064772

Synonyms:

Ala-Gly-cyclo[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys] (SRIF14) | CHEMBL408362

Type

Small organic molecule

Emp. Form.

C76H104N18O19S2

Mol. Mass.

1637.878

SMILES

C[C@@H](O)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O

Structure