| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosylhomocysteinase |
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| Ligand | BDBM50369381 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_196552 (CHEMBL801947) |
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| Ki | 3600±n/a nM |
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| Citation |  Wnuk, SF; Mao, Y; Yuan, CS; Borchardt, RT; Andrei, G; Balzarini, J; De Clercq, E; Robins, MJ Discovery of type II (covalent) inactivation of S-adenosyl-L-homocysteine hydrolase involving its"hydrolytic activity": synthesis and evaluation of dihalohomovinyl nucleoside analogues derived from adenosine. J Med Chem41:3078-83 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosylhomocysteinase |
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| Name: | Adenosylhomocysteinase |
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| Synonyms: | AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47714.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507791 |
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| Residue: | 432 |
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| Sequence: | MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVET
AVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYF
KDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINV
NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI
ITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIG
HFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSN
SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMS
CDGPFKPDHYRY
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| BDBM50369381 |
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| n/a |
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| Name | BDBM50369381 |
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| Synonyms: | CHEMBL612194 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H11Br2N5O3 |
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| Mol. Mass. | 421.045 |
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| SMILES | Nc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(\Br)=C/Br |r| |
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| Structure | 
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