| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50067069 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_41032 (CHEMBL651936) |
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| IC50 | 26±n/a nM |
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| Citation |  Hubschwerlen, C; Angehrn, P; Gubernator, K; Page, MG; Specklin, JL Structure-based design of beta-lactamase inhibitors. 2. Synthesis and evaluation of bridged sulfactams and oxamazins. J Med Chem41:3972-5 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | AMPC_ENTCL | ampC |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41306.67 |
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| Organism: | Enterobacter cloacae |
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| Description: | ChEMBL_40258 |
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| Residue: | 381 |
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| Sequence: | MMRKSLCCALLLGISCSALATPVSEKQLAEVVANTITPLMKAQSVPGMAVAVIYQGKPHY
YTFGKADIAANKPVTPQTLFELGSISKTFTGVLGGDAIARGEISLDDAVTRYWPQLTGKQ
WQGIRMLDLATYTAGGLPLQVPDEVTDNASLLRFYQNWQPQWKPGTTRLYANASIGLFGA
LAVKPSGMPYEQAMTTRVLKPLKLDHTWINVPKAEEAHYAWGYRDGKAVRVSPGMLDAQA
YGVKTNVQDMANWVMANMAPENVADASLKQGIALAQSRYWRIGSMYQGLGWEMLNWPVEA
NTVVEGSDSKVALAPLPVAEVNPPAPPVKASWVHKTGSTGGFGSYVAFIPEKQIGIVMLA
NTSYPNPARVEAAYHILEALQ
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| BDBM50067069 |
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| n/a |
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| Name | BDBM50067069 |
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| Synonyms: | CHEMBL128220 | sodium salt-Sulfuric acid mono-[2-(4-carbamoyl-phenylcarbamoyl)-7-oxo-2,6-diaza-bicyclo[3.2.0]hept-6-yl] ester |
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| Type | Small organic molecule |
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| Emp. Form. | C13H13N4O7S |
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| Mol. Mass. | 369.33 |
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| SMILES | NC(=O)c1ccc(NC(=O)N2CCC3C2C(=O)N3OS([O-])(=O)=O)cc1 |
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| Structure | 
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