| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM84637 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_61319 (CHEMBL670094) |
|---|
| Ki | 59±n/a nM |
|---|
| Citation |  Cervetto, L; Demontis, GC; Giannaccini, G; Longoni, B; Macchia, B; Macchia, M; Martinelli, A; Orlandini, E N-n-Propyl-substituted 3-(dimethylphenyl)piperidines display novel discriminative properties between dopamine receptor subtypes: synthesis and receptor binding studies. J Med Chem41:4933-8 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 50698.79 |
|---|
| Organism: | BOVINE |
|---|
| Description: | P20288 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFLKILHC
|
|
|
|---|
| BDBM84637 |
|---|
| n/a |
|---|
| Name | BDBM84637 |
|---|
| Synonyms: | CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPIROLE | Quinpirole,(-) | US9359372, Quinpirole |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H21N3 |
|---|
| Mol. Mass. | 219.3259 |
|---|
| SMILES | CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
