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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Progesterone receptor | ||
| Ligand | BDBM50062439 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_159558 (CHEMBL765846) | ||
| Ki | 0.500000±n/a nM | ||
| Citation |  Edwards, JP; West, SJ; Marschke, KB; Mais, DE; Gottardis, MM; Jones, TK 5-Aryl-1,2-dihydro-5H-chromeno[3,4-f]quinolines as potent, orally active, nonsteroidal progesterone receptor agonists: the effect of D-ring substituents. J Med Chem41:303-10 (1998) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Progesterone receptor | |||
| Name: | Progesterone receptor | ||
| Synonyms: | NR3C3 | Nuclear receptor subfamily 3 group C member 3 | PGR | PR | PRGR_HUMAN | progesterone | ||
| Type: | Protein | ||
| Mol. Mass.: | 98979.52 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P06401 | ||
| Residue: | 933 | ||
| Sequence: |
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| BDBM50062439 | |||
| n/a | |||
| Name | BDBM50062439 | ||
| Synonyms: | 9-Chloro-5-(4-chloro-3-methyl-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene | CHEMBL94753 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H23Cl2NO | ||
| Mol. Mass. | 436.373 | ||
| SMILES | CC1=CC(C)(C)Nc2ccc3-c4cc(Cl)ccc4OC(c4ccc(Cl)c(C)c4)c3c12 |t:1,(12.82,-5.82,;14.16,-6.59,;15.49,-7.36,;15.49,-8.9,;15.48,-10.44,;16.82,-8.13,;14.15,-9.66,;12.82,-8.89,;11.48,-9.66,;10.15,-8.87,;10.16,-7.35,;8.82,-6.58,;7.49,-7.35,;6.16,-6.58,;4.83,-7.35,;6.16,-5.04,;7.49,-4.27,;8.83,-5.04,;10.16,-4.25,;11.5,-5.04,;12.83,-4.27,;12.83,-2.74,;14.16,-1.97,;15.5,-2.74,;16.85,-1.98,;15.49,-4.29,;16.83,-5.06,;14.16,-5.05,;11.5,-6.58,;12.82,-7.35,)| | ||
| Structure | 
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