| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50369433 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_212879 (CHEMBL824707) |
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| Ki | 55±n/a nM |
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| Citation |  Quan, ML; Liauw, AY; Ellis, CD; Pruitt, JR; Carini, DJ; Bostrom, LL; Huang, PP; Harrison, K; Knabb, RM; Thoolen, MJ; Wong, PC; Wexler, RR Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 1. J Med Chem42:2752-9 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM50369433 |
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| n/a |
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| Name | BDBM50369433 |
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| Synonyms: | CHEMBL1202108 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H33BN6O5 |
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| Mol. Mass. | 460.335 |
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| SMILES | [#6]-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@@H]-1-[#6](=O)-[#7]-[#6](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#5](-[#8])-[#8] |r| |
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| Structure | 
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