| Reaction Details |
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 | Report a problem with these data |
| Target | Anionic trypsin |
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| Ligand | BDBM50080503 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_212180 (CHEMBL817744) |
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| Ki | 1390±n/a nM |
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| Citation |  Ewing, WR; Becker, MR; Manetta, VE; Davis, RS; Pauls, HW; Mason, H; Choi-Sledeski, YM; Green, D; Cha, D; Spada, AP; Cheney, DL; Mason, JS; Maignan, S; Guilloteau, JP; Brown, K; Colussi, D; Bentley, R; Bostwick, J; Kasiewski, CJ; Morgan, SR; Leadley, RJ; Dunwiddie, CT; Perrone, MH; Chu, V Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor Xa. J Med Chem42:3557-71 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Anionic trypsin |
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| Name: | Anionic trypsin |
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| Synonyms: | Anionic trypsin | TRY2_BOVIN | Trypsin II |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26281.39 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_212177 |
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| Residue: | 247 |
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| Sequence: | MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVS
AAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVIN
ARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQIT
NNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQ
ETIAANS
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| BDBM50080503 |
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| n/a |
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| Name | BDBM50080503 |
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| Synonyms: | 3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-(1H-pyrazol-3-ylmethyl)-amino]-2-oxo-pyrrolidin-1-ylmethyl}-benzamidine | CHEMBL119964 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H28N6O4S |
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| Mol. Mass. | 532.614 |
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| SMILES | COc1ccc2ccc(cc2c1)S(=O)(=O)N(Cc1ccn[nH]1)[C@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O |
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| Structure | 
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