| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50271991 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_145851 (CHEMBL756114) |
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| IC50 | 524±n/a nM |
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| Citation |  Houghten, RA; Pinilla, C; Appel, JR; Blondelle, SE; Dooley, CT; Eichler, J; Nefzi, A; Ostresh, JM Mixture-based synthetic combinatorial libraries. J Med Chem42:3743-78 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM50271991 |
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| n/a |
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| Name | BDBM50271991 |
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| Synonyms: | (2S,5R)-1-(2-{bicyclo[2.2.1]heptan-2-yl}ethyl)-2,5-dicyclohexyl-1H,2H,3H,5H,6H-imidazo[1,2-a]imidazolidin-7-ium | (2S,5S)-1-(2-{bicyclo[2.2.1]heptan-2-yl}ethyl)-2,5-dicyclohexyl-1H,2H,3H,5H,6H-imidazo[1,2-a]imidazolidin-7-ium |
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| Type | Small organic molecule |
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| Emp. Form. | C26H44N3 |
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| Mol. Mass. | 398.6471 |
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| SMILES | C(CN1C(C[N+]2=C1NCC2C1CCCCC1)C1CCCCC1)C1CC2CCC1C2 |c:5,THB:0:22:28:26.25| |
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| Structure | 
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