| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50081371 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_201434 (CHEMBL809837) |
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| IC50 | 4.5±n/a nM |
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| Citation |  Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Synthesis and SAR of 1-alkyl-2-phenylethylamine derivatives designed from N,N-dipropyl-4-methoxy-3-(2-phenylethoxy)phenylethylamine to discover sigma(1) ligands. J Med Chem42:3965-70 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50081371 |
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| n/a |
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| Name | BDBM50081371 |
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| Synonyms: | CHEMBL128799 | [1-(4-Methoxy-3-phenethyloxy-benzyl)-butyl]-propyl-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C23H33NO2 |
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| Mol. Mass. | 355.5136 |
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| SMILES | CCCNC(CCC)Cc1ccc(OC)c(OCCc2ccccc2)c1 |
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| Structure | 
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