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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | C-C chemokine receptor type 1 | ||
| Ligand | BDBM50082670 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_41751 (CHEMBL651702) | ||
| Ki | 6±n/a nM | ||
| Citation |  Ng, HP; May, K; Bauman, JG; Ghannam, A; Islam, I; Liang, M; Horuk, R; Hesselgesser, J; Snider, RM; Perez, HD; Morrissey, MM Discovery of novel non-peptide CCR1 receptor antagonists. J Med Chem42:4680-94 (1999) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| C-C chemokine receptor type 1 | |||
| Name: | C-C chemokine receptor type 1 | ||
| Synonyms: | C-C CKR-1 | C-C chemokine receptor type 1 (CCR1) | CC-CKR-1 | CCR-1 | CCR1 | CCR1_HUMAN | CD_antigen=CD191 | CMKBR1 | CMKR1 | HM145 | LD78 receptor | MIP-1alpha-R | Macrophage inflammatory protein 1-alpha receptor | RANTES-R | SCYAR1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 41180.69 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P32246 | ||
| Residue: | 355 | ||
| Sequence: |
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| BDBM50082670 | |||
| n/a | |||
| Name | BDBM50082670 | ||
| Synonyms: | 4-(4-Chloro-phenyl)-1-(4,4-diphenyl-butyl)-4-hydroxy-1-methyl-piperidinium; iodide | CHEMBL356099 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H33ClNO | ||
| Mol. Mass. | 435.02 | ||
| SMILES | C[N+]1(CCCC(c2ccccc2)c2ccccc2)CCC(O)(CC1)c1ccc(Cl)cc1 |(4.39,-16.36,;5.59,-14.67,;4.76,-13.8,;4.76,-12.26,;3.43,-11.48,;3.43,-9.94,;2.64,-8.61,;3.41,-7.25,;2.64,-5.9,;1.07,-5.91,;.3,-7.26,;1.09,-8.61,;2.1,-10.69,;2.06,-12.23,;.74,-12.97,;-.6,-12.19,;-.58,-10.65,;.77,-9.89,;6.81,-15.92,;8.35,-15.99,;9.17,-14.69,;10.24,-13.6,;8.45,-13.32,;6.91,-13.28,;10.24,-15.76,;9.85,-17.24,;10.92,-18.3,;12.38,-17.91,;13.45,-19,;12.78,-16.43,;11.71,-15.38,)| | ||
| Structure | 
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