| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM50083322 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_144589 (CHEMBL749506) |
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| Ki | 0.39±n/a nM |
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| Citation |  Wall, ID; Leach, AR; Salt, DW; Ford, MG; Essex, JW Binding constants of neuraminidase inhibitors: An investigation of the linear interaction energy method. J Med Chem42:5142-52 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | Influenza A Virus Neuraminidase | NA | NRAM_I34A1 | Neuraminidase | Neuraminidase A |
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| Type: | Enzyme |
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| Mol. Mass.: | 50124.14 |
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| Organism: | Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) |
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| Description: | P03468 |
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| Residue: | 454 |
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| Sequence: | MNPNQKIITIGSICLVVGLISLILQIGNIISIWISHSIQTGSQNHTGICNQNIITYKNST
WVKDTTSVILTGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLT
QGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGI
SGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECACVNGSCFTIMTDGPSDGLASYKI
FKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIG
YICSGVFGDNPRPEDGTGSCGPVYVDGANGVKGFSYRYGNGVWIGRTKSHSSRHGFEMIW
DPNGWTETDSKFSVRQDVVAMTDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPKEKT
IWTSASSISFCGVNSDTVDWSWPDGAELPFSIDK
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| BDBM50083322 |
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| n/a |
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| Name | BDBM50083322 |
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| Synonyms: | 3-Acetylamino-2-diethylcarbamoyl-6-dihydroxymethyl-3,4-dihydro-2H-pyran-4-yl-ammonium |
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| Type | Small organic molecule |
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| Emp. Form. | C13H24N3O5 |
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| Mol. Mass. | 302.3462 |
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| SMILES | CCN(CC)C(=O)[C@@H]1OC(=C[C@H]([NH3+])[C@H]1NC(C)=O)C(O)O |c:9| |
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| Structure | 
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