| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50073503 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_138287 (CHEMBL744319) |
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| IC50 | 18±n/a nM |
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| Citation |  Augelli-Szafran, CE; Blankley, CJ; Jaen, JC; Moreland, DW; Nelson, CB; Penvose-Yi, JR; Schwarz, RD; Thomas, AJ Identification and characterization of m1 selective muscarinic receptor antagonists1. J Med Chem42:356-63 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1 |
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| Type: | Protein |
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| Mol. Mass.: | 51442.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11229 |
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| Residue: | 460 |
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| Sequence: | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50073503 |
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| n/a |
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| Name | BDBM50073503 |
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| Synonyms: | 1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid cyclohexyl ester; oxalic acid | CHEMBL332980 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H27NO2 |
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| Mol. Mass. | 313.4339 |
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| SMILES | CCN1CCC(=C(C1)C(=O)OC1CCCCC1)c1ccccc1 |c:5| |
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| Structure | 
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