| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM50073468 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_139631 (CHEMBL748244) |
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| IC50 | 73±n/a nM |
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| Citation |  Augelli-Szafran, CE; Blankley, CJ; Jaen, JC; Moreland, DW; Nelson, CB; Penvose-Yi, JR; Schwarz, RD; Thomas, AJ Identification and characterization of m1 selective muscarinic receptor antagonists1. J Med Chem42:356-63 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_HUMAN | CHRM2 | Cholinergic, muscarinic M2 | Muscarinic acetylcholine receptor M2 and M4 | Muscarinic acetylcholine receptor M2 and M5 | RecName: Full=Muscarinic acetylcholine receptor M2 |
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| Type: | GPCR |
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| Mol. Mass.: | 51730.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08172 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM50073468 |
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| n/a |
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| Name | BDBM50073468 |
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| Synonyms: | 1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid heptyl ester; oxalic acid | CHEMBL334245 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H31NO2 |
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| Mol. Mass. | 329.4763 |
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| SMILES | CCCCCCCOC(=O)C1=C(CCN(CC)C1)c1ccccc1 |t:10| |
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| Structure | 
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