| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2Y purinoceptor 1 |
|---|
| Ligand | BDBM50076459 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_147715 (CHEMBL759185) |
|---|
| EC50 | 1980±n/a nM |
|---|
| Citation |  Nandanan, E; Camaioni, E; Jang, SY; Kim, YC; Cristalli, G; Herdewijn, P; Secrist, JA; Tiwari, KN; Mohanram, A; Harden, TK; Boyer, JL; Jacobson, KA Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists. J Med Chem42:1625-38 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2Y purinoceptor 1 |
|---|
| Name: | P2Y purinoceptor 1 |
|---|
| Synonyms: | P2RY1 | P2RY1_MELGA |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 41199.64 |
|---|
| Organism: | Meleagris gallopavo |
|---|
| Description: | n/a |
|---|
| Residue: | 362 |
|---|
| Sequence: | MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSV
AIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIF
HVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSG
TGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDN
SPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRG
LASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDT
SL
|
|
|
|---|
| BDBM50076459 |
|---|
| n/a |
|---|
| Name | BDBM50076459 |
|---|
| Synonyms: | CHEMBL43868 | Phosphoric acid mono-[5-(6-amino-2-ethylsulfanyl-purin-9-yl)-2-phosphonooxymethyl-tetrahydro-furan-3-yl] ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H19N5O9P2S |
|---|
| Mol. Mass. | 471.32 |
|---|
| SMILES | CCSc1nc(N)c2ncn(C3CC(OP(O)(O)=O)C(COP(O)(O)=O)O3)c2n1 |
|---|
| Structure | 
|
|---|
Search and Browse
