| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50088380 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_146677 (CHEMBL753169) |
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| Ki | 1±n/a nM |
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| Citation |  Lavecchia, A; Greco, G; Novellino, E; Vittorio, F; Ronsisvalle, G Modeling of kappa-opioid receptor/agonists interactions using pharmacophore-based and docking simulations. J Med Chem43:2124-34 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42744.99 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | P41144 |
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| Residue: | 380 |
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| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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| BDBM50088380 |
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| n/a |
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| Name | BDBM50088380 |
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| Synonyms: | 1-(1-{[2-(3,4-Dichloro-phenyl)-acetyl]-methyl-amino}-6-hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-pyrrolidinium |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27Cl2N2O2 |
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| Mol. Mass. | 434.378 |
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| SMILES | CN([C@@H]1[C@H](CCc2cc(O)ccc12)[NH+]1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |
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| Structure | 
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