| Reaction Details |
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 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 6 |
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| Ligand | BDBM50060719 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_104311 (CHEMBL718130) |
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| Ki | 58000±n/a nM |
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| Citation |  Bräuner-Osborne, H; Egebjerg, J; Nielsen, EO; Madsen, U; Krogsgaard-Larsen, P Ligands for glutamate receptors: design and therapeutic prospects. J Med Chem43:2609-45 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Metabotropic glutamate receptor 6 |
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| Name: | Metabotropic glutamate receptor 6 |
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| Synonyms: | GPRC1F | GRM6 | GRM6_HUMAN | MGLUR6 | Metabotropic glutamate receptor 6 | glutamate receptor, metabotropic 6 precursor | metabotropic glutamate 6 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 95479.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | metabotropic glutamate 6 GRM6 HUMAN::O15303 |
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| Residue: | 877 |
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| Sequence: | MARPRRAREPLLVALLPLAWLAQAGLARAAGSVRLAGGLTLGGLFPVHARGAAGRACGQL
KKEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGR
GDGDEVGVRCPGGVPPLRPAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPE
LSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREA
GGVCIAQSIKIPREPKPGEFSKVIRRLMETPNARGIIIFANEDDIRRVLEAARQANLTGH
FLWVGSDSWGAKTSPILSLEDVAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEF
WEENFNCKLTSSGTQSDDSTRKCTGEERIGRDSTYEQEGKVQFVIDAVYAIAHALHSMHQ
ALCPGHTGLCPAMEPTDGRMLLQYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNG
SASSGGYQAVGQWAETLRLDVEALQWSGDPHEVPSSLCSLPCGPGERKKMVKGVPCCWHC
EACDGYRFQVDEFTCEACPGDMRPTPNHTGCRPTPVVRLSWSSPWAAPPLLLAVLGIVAT
TTVVATFVRYNNTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPGAAVCAARRLFLGLG
TTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFSLTSLQVVGMIAWLGARP
PHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFN
EAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKT
YVILFHPEQNVQKRKRSLKATSTVAAPPKGEDAEAHK
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| BDBM50060719 |
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| n/a |
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| Name | BDBM50060719 |
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| Synonyms: | (S)-2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid | 2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid | 2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid(S-homo-AMPA) | CHEMBL315268 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H12N2O4 |
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| Mol. Mass. | 200.1919 |
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| SMILES | Cc1o[nH]c(=O)c1CC[C@H](N)C(O)=O |
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| Structure | 
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