| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A3 |
|---|
| Ligand | BDBM50090700 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_31246 (CHEMBL642211) |
|---|
| Ki | 2100±n/a nM |
|---|
| Citation |  Ferrarini, PL; Mori, C; Manera, C; Martinelli, A; Mori, F; Saccomanni, G; Barili, PL; Betti, L; Giannaccini, G; Trincavelli, L; Lucacchini, A A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives. J Med Chem43:2814-23 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A3 |
|---|
| Name: | Adenosine receptor A3 |
|---|
| Synonyms: | AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 36643.73 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_479910 |
|---|
| Residue: | 320 |
|---|
| Sequence: | MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALAD
IAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRY
RTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMV
FFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFL
FALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILR
ACRLCQTSDSLDSNLEQTTE
|
|
|
|---|
| BDBM50090700 |
|---|
| n/a |
|---|
| Name | BDBM50090700 |
|---|
| Synonyms: | 7-Bromo-2-phenyl-[1,8]naphthyridin-4-ol | 7-bromo-2-phenyl-1,8-naphthyridin-4-ol | CHEMBL97687 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H9BrN2O |
|---|
| Mol. Mass. | 301.138 |
|---|
| SMILES | Oc1cc(nc2nc(Br)ccc12)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
