| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2a |
|---|
| Ligand | BDBM50090698 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_31046 (CHEMBL642117) |
|---|
| Ki | 1800±n/a nM |
|---|
| Citation |  Ferrarini, PL; Mori, C; Manera, C; Martinelli, A; Mori, F; Saccomanni, G; Barili, PL; Betti, L; Giannaccini, G; Trincavelli, L; Lucacchini, A A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives. J Med Chem43:2814-23 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2a |
|---|
| Name: | Adenosine receptor A2a |
|---|
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44716.46 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P29274 |
|---|
| Residue: | 412 |
|---|
| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
|
|
|
|---|
| BDBM50090698 |
|---|
| n/a |
|---|
| Name | BDBM50090698 |
|---|
| Synonyms: | (7-Methyl-2-phenyl-[1,8]naphthyridin-4-yl)-hydrazine | 1-(7-methyl-2-phenyl-1,8-naphthyridin-4-yl)hydrazine | CHEMBL94538 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H14N4 |
|---|
| Mol. Mass. | 250.2985 |
|---|
| SMILES | Cc1ccc2c(NN)cc(nc2n1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
