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TargetHuman immunodeficiency virus type 1 protease
LigandBDBM50366785
Substrate/Competitorn/a
Meas. Tech.ChEMBL_222918
Ki 27±n/a nM
Citation Dorsey BDMcDonough CMcDaniel SLLevin RBNewton CLHoffman JMDarke PLZugay-Murphy JAEmini EASchleif WAOlsen DBStahlhut MWRutkowski CAKuo LCLin JHChen IWMichelson SRHolloway MKHuff JRVacca JP Identification of MK-944a: a second clinical candidate from the hydroxylaminepentanamide isostere series of HIV protease inhibitors. J Med Chem 43:3386-99 (2000) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 protease
Name:Human immunodeficiency virus type 1 protease
Synonyms:Pol polyprotein
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:n/a
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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  Blast E-value cutoff:
BDBM50366785
n/a
NameBDBM50366785
Synonyms:NELFINAVIR
TypeSmall organic molecule
Emp. Form.C32H45N3O4S
Mol. Mass.567.782
SMILESCc1c(O)cccc1C(=O)N[C@H](CSc1ccccc1)[C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C |r|
Structure
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