| Reaction Details |
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 | Report a problem with these data |
| Target | Renin |
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| Ligand | BDBM50084615 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_195962 (CHEMBL806856) |
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| IC50 | 13±n/a nM |
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| Citation |  Leung, D; Abbenante, G; Fairlie, DP Protease inhibitors: current status and future prospects. J Med Chem43:305-41 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Renin |
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| Name: | Renin |
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| Synonyms: | Angiotensinogenase | REN | RENI_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 45058.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 406 |
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| Sequence: | MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEW
SQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRL
YTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEM
PALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGG
QIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISG
STSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKK
LCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR
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| BDBM50084615 |
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| n/a |
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| Name | BDBM50084615 |
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| Synonyms: | (4S,5S,7S)-5-Amino-7-(4-tert-butyl-3-methanesulfonylmethoxy-benzyl)-4-hydroxy-2,8-dimethyl-nonanoic acid butylamide | 5-Amino-7-(4-tert-butyl-3-methanesulfonylmethoxy-benzyl)-4-hydroxy-2,8-dimethyl-nonanoic acid butylamide | CHEMBL433218 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H50N2O5S |
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| Mol. Mass. | 526.772 |
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| SMILES | CCCCNC(=O)C(C)C[C@H](O)[C@@H](N)C[C@H](Cc1ccc(c(OCS(C)(=O)=O)c1)C(C)(C)C)C(C)C |
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| Structure | 
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