| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine protease 1 |
|---|
| Ligand | BDBM50084616 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_213067 (CHEMBL817134) |
|---|
| Ki | 84000±n/a nM |
|---|
| Citation |  Leung, D; Abbenante, G; Fairlie, DP Protease inhibitors: current status and future prospects. J Med Chem43:305-41 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine protease 1 |
|---|
| Name: | Serine protease 1 |
|---|
| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 26557.80 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07477 |
|---|
| Residue: | 247 |
|---|
| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
|
|
|
|---|
| BDBM50084616 |
|---|
| n/a |
|---|
| Name | BDBM50084616 |
|---|
| Synonyms: | CHEMBL310290 | [(4-Aminomethyl-benzylcarbamoyl)-methyl]-carbamic acid 4-[(4-aminomethyl-benzylcarbamoyl)-methylcarbamoyloxymethyl]-benzyl ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H36N6O6 |
|---|
| Mol. Mass. | 576.6434 |
|---|
| SMILES | NCc1ccc(CNC(=O)CNC(=O)OCc2ccc(COC(=O)NCC(=O)NCc3ccc(CN)cc3)cc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
