| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Procathepsin L |
|---|
| Ligand | BDBM50084677 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_216708 (CHEMBL820320) |
|---|
| IC50 | 1.9±n/a nM |
|---|
| Citation |  Leung, D; Abbenante, G; Fairlie, DP Protease inhibitors: current status and future prospects. J Med Chem43:305-41 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Procathepsin L |
|---|
| Name: | Procathepsin L |
|---|
| Synonyms: | CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 37557.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Purchased from Calbiochem (San Diego, CA). |
|---|
| Residue: | 333 |
|---|
| Sequence: | MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
|
|
|
|---|
| BDBM50084677 |
|---|
| n/a |
|---|
| Name | BDBM50084677 |
|---|
| Synonyms: | 3-Methyl-2-(naphthalene-1-sulfonylamino)-pentanoic acid [1-formyl-2-(1H-indol-3-yl)-ethyl]-amide | CHEMBL115676 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H29N3O4S |
|---|
| Mol. Mass. | 491.602 |
|---|
| SMILES | CCC(C)[C@H](NS(=O)(=O)c1cccc2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C=O |
|---|
| Structure | 
|
|---|
Search and Browse
