| Reaction Details |
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 | Report a problem with these data |
| Target | Calpain-1 catalytic subunit |
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| Ligand | BDBM50084684 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_217824 (CHEMBL821731) |
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| Ki | 41000±n/a nM |
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| Citation |  Leung, D; Abbenante, G; Fairlie, DP Protease inhibitors: current status and future prospects. J Med Chem43:305-41 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Calpain-1 catalytic subunit |
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| Name: | Calpain-1 catalytic subunit |
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| Synonyms: | CAN1_HUMAN | CANPL1 | CAPN1 | Calpain ยต-type | Calpain-1 (u-Calpain) | Calpain-1 catalytic subunit | Calpain1 |
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| Type: | Protein |
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| Mol. Mass.: | 81880.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 714 |
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| Sequence: | MSEEIITPVYCTGVSAQVQKQRARELGLGRHENAIKYLGQDYEQLRVRCLQSGTLFRDEA
FPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAA
IASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHS
AEGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILK
ALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYRGQVVSLIRMRNPWGE
VEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKS
RTIRKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGDRESGCSFV
LALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFINL
REVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQANLPDEQVLSE
EEIDENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRD
GNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELII
TRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA
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| BDBM50084684 |
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| n/a |
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| Name | BDBM50084684 |
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| Synonyms: | CHEMBL333627 | {3-Methyl-1-[1-(3-morpholin-4-yl-propylaminooxalyl)-propylcarbamoyl]-butyl}-carbamic acid benzyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C26H40N4O6 |
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| Mol. Mass. | 504.619 |
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| SMILES | CC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCCCN1CCOCC1 |
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| Structure | 
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