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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Prothrombin | ||
| Ligand | BDBM50062632 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_208886 (CHEMBL814943) | ||
| Ki | 1.5±n/a nM | ||
| Citation |  Leung, D; Abbenante, G; Fairlie, DP Protease inhibitors: current status and future prospects. J Med Chem43:305-41 (2000) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Prothrombin | |||
| Name: | Prothrombin | ||
| Synonyms: | Activation peptide fragment 1 | Activation peptide fragment 2 | Coagulation factor II | F2 | Prothrombin precursor | THRB_HUMAN | Thrombin heavy chain | Thrombin light chain | ||
| Type: | Protein | ||
| Mol. Mass.: | 70029.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P00734 | ||
| Residue: | 622 | ||
| Sequence: |
| ||
| BDBM50062632 | |||
| n/a | |||
| Name | BDBM50062632 | ||
| Synonyms: | (S)-1-(9-Hydroxy-9H-fluorene-9-carbonyl)-pyrrolidine-2-carboxylic acid (4-amino-cyclohexylmethyl)-amide | 1-(9-Hydroxy-9H-fluorene-9-carbonyl)-pyrrolidine-2-carboxylic acid (4-amino-cyclohexylmethyl)-amide(L-372,460) | CHEMBL262967 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H31N3O3 | ||
| Mol. Mass. | 433.5426 | ||
| SMILES | NC1CCC(CNC(=O)[C@@H]2CCCN2C(=O)C2(O)c3ccccc3-c3ccccc23)CC1 |wU:9.8,(14.19,2.05,;14.19,.5,;12.85,-.27,;11.75,-1.35,;10.61,-.46,;9.27,-1.25,;7.92,-.46,;6.6,-1.25,;6.6,-2.79,;5.26,-.46,;5.74,1.01,;4.49,1.91,;3.25,1.01,;3.73,-.46,;2.38,-1.25,;2.38,-2.8,;1.06,-.48,;1.04,-2.03,;.88,1.06,;1.9,2.2,;1.42,3.67,;-.09,3.99,;-1.11,2.84,;-.63,1.38,;-1.4,.05,;-2.9,-.27,;-3.38,-1.73,;-2.34,-2.88,;-.85,-2.56,;-.37,-1.1,;12.11,-.06,;12.85,1.27,)| | ||
| Structure | 
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