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TargetMelatonin receptor type 1B
LigandBDBM50086005
Substrate/Competitorn/a
Meas. Tech.ChEMBL_105265 (CHEMBL872558)
Ki 0.51±n/a nM
Citation Faust, RGarratt, PJJones, RYeh, LKTsotinis, APanoussopoulou, MCalogeropoulou, TTeh, MTSugden, D Mapping the melatonin receptor. 6. Melatonin agonists and antagonists derived from 6H-isoindolo[2,1-a]indoles, 5,6-dihydroindolo[2,1-a]isoquinolines, and 6,7-dihydro-5H-benzo[c]azepino[2,1-a]indoles. J Med Chem43:1050-61 (2000) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor type 1B
Name:Melatonin receptor type 1B
Synonyms:MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:Enzyme
Mol. Mass.:40203.54
Organism:Homo sapiens (Human)
Description:P49286
Residue:362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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BDBM50086005
n/a
NameBDBM50086005
Synonyms:CHEMBL274842 | N-[2-(10-Methoxy-5,6-dihydro-indolo[2,1-a]isoquinolin-12-yl)-ethyl]-acetamide
TypeSmall organic molecule
Emp. Form.C21H22N2O2
Mol. Mass.334.4116
SMILESCOc1ccc2n3CCc4ccccc4-c3c(CCNC(C)=O)c2c1
Structure
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