| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM50086003 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_105101 (CHEMBL715945) |
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| Ki | 115±n/a nM |
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| Citation |  Faust, R; Garratt, PJ; Jones, R; Yeh, LK; Tsotinis, A; Panoussopoulou, M; Calogeropoulou, T; Teh, MT; Sugden, D Mapping the melatonin receptor. 6. Melatonin agonists and antagonists derived from 6H-isoindolo[2,1-a]indoles, 5,6-dihydroindolo[2,1-a]isoquinolines, and 6,7-dihydro-5H-benzo[c]azepino[2,1-a]indoles. J Med Chem43:1050-61 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50086003 |
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| n/a |
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| Name | BDBM50086003 |
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| Synonyms: | CHEMBL9838 | N-[2-(6,7-Dihydro-5H-benzo[3,4]azepino[1,2-a]indol-13-yl)-ethyl]-propionamide |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24N2O |
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| Mol. Mass. | 332.4388 |
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| SMILES | CCC(=O)NCCc1c2-c3ccccc3CCCn2c2ccccc12 |
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| Structure | 
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