| Reaction Details |
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 | Report a problem with these data |
| Target | E-selectin |
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| Ligand | BDBM50408284 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_199877 (CHEMBL803778) |
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| IC50 | 280000±n/a nM |
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| Citation |  Hiramatsu, Y; Tsukida, T; Nakai, Y; Inoue, Y; Kondo, H Study on selectin blocker. 8. Lead discovery of a non-sugar antagonist using a 3D-pharmacophore model. J Med Chem43:1476-83 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| E-selectin |
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| Name: | E-selectin |
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| Synonyms: | Elam-1 | LYAM2_MOUSE | Sele | Selectin E |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66749.86 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_199837 |
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| Residue: | 612 |
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| Sequence: | MNASRFLSALVFVLLAGESTAWYYNASSELMTYDEASAYCQRDYTHLVAIQNKEEINYLN
SNLKHSPSYYWIGIRKVNNVWIWVGTGKPLTEEAQNWAPGEPNNKQRNEDCVEIYIQRTK
DSGMWNDERCNKKKLALCYTASCTNASCSGHGECIETINSYTCKCHPGFLGPNCEQAVTC
KPQEHPDYGSLNCSHPFGPFSYNSSCSFGCKRGYLPSSMETTVRCTSSGEWSAPAPACHV
VECEALTHPAHGIRKCSSNPGSYPWNTTCTFDCVEGYRRVGAQNLQCTSSGIWDNETPSC
KAVTCDAIPQPQNGFVSCSHSTAGELAFKSSCNFTCEQSFTLQGPAQVECSAQGQWTPQI
PVCKAVQCEALSAPQQGNMKCLPSASGPFQNGSSCEFSCEEGFELKGSRRLQCGPRGEWD
SKKPTCSAVKCDDVPRPQNGVMECAHATTGEFTYKSSCAFQCNEGFSLHGSAQLECTSQG
KWTQEVPSCQVVQCPSLDVPGKMNMSCSGTAVFGTVCEFTCPDDWTLNGSAVLTCGATGR
WSGMPPTCEAPVSPTRPLVVALSAAGTSLLTSSSLLYLLMRYFRKKAKKFVPASSCQSLQ
SFENYHVPSYNV
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| BDBM50408284 |
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| n/a |
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| Name | BDBM50408284 |
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| Synonyms: | CHEMBL2029056 |
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| Type | Small organic molecule |
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| Emp. Form. | C48H91O18S |
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| Mol. Mass. | 988.291 |
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| SMILES | CCCCCCCCCCCCCCC(CCCCCCCCCCCCCC)CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](OS([O-])(=O)=O)[C@H]2O)[C@H](O[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)[C@H]1O |r| |
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| Structure | 
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