| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium/glucose cotransporter 1 |
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| Ligand | BDBM50422346 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_202730 (CHEMBL809058) |
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| Ki | 23100±n/a nM |
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| Citation |  Wielert-Badt, S; Lin, JT; Lorenz, M; Fritz, S; Kinne, RK Probing the conformation of the sugar transport inhibitor phlorizin by 2D-NMR, molecular dynamics studies, and pharmacophore analysis. J Med Chem43:1692-8 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium/glucose cotransporter 1 |
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| Name: | Sodium/glucose cotransporter 1 |
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| Synonyms: | High affinity sodium-glucose cotransporter | NAGT | Na(+)/glucose cotransporter 1 | SC5A1_HUMAN | SGLT1 | SLC5A1 | Sodium-dependent glucose cotransporter 1 (SGLT1) | Sodium/glucose cotransporter 1 | Sodium/glucose cotransporter 1 (SGLT1) | Solute carrier family 5 member 1 |
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| Type: | Protein |
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| Mol. Mass.: | 73503.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P13866 |
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| Residue: | 664 |
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| Sequence: | MDSSTWSPKTTAVTRPVETHELIRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFL
AGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIY
IKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLA
IFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAI
PTIVSDGNTTFQEKCYTPRADSFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQR
CLSAKNMSHVKGGCILCGYLKLMPMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVG
CTNIAYPTLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEK
ELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRV
NEPGAFWGLILGLLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFIT
IVVISLLTKPIPDVHLYRLCWSLRNSKEERIDLDAEEENIQEGPKETIEIETQVPEKKKG
IFRRAYDLFCGLEQHGAPKMTEEEEKAMKMKMTDTSEKPLWRTVLNVNGIILVTVAVFCH
AYFA
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| BDBM50422346 |
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| n/a |
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| Name | BDBM50422346 |
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| Synonyms: | CHEMBL2303991 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21Br3O10 |
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| Mol. Mass. | 673.097 |
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| SMILES | OC[C@@H]1O[C@@H](Oc2cc(O)c(Br)c(O)c2C(=O)CCc2cc(Br)c(O)c(Br)c2)[C@@H](O)[C@@H](O)[C@@H]1O |r| |
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| Structure | 
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