| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Delta-type opioid receptor |
|---|
| Ligand | BDBM50026889 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_145308 (CHEMBL751914) |
|---|
| EC50 | 19±n/a nM |
|---|
| Citation |  Coop, A; Norton, CL; Berzetei-Gurske, I; Burnside, J; Toll, L; Husbands, SM; Lewis, JW Structural determinants of opioid activity in the orvinols and related structures: ethers of orvinol and isoorvinol. J Med Chem43:1852-7 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Delta-type opioid receptor |
|---|
| Name: | Delta-type opioid receptor |
|---|
| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 40382.98 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
|---|
| Residue: | 372 |
|---|
| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
|
|
|
|---|
| BDBM50026889 |
|---|
| n/a |
|---|
| Name | BDBM50026889 |
|---|
| Synonyms: | CHEMBL2113672 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H33NO4 |
|---|
| Mol. Mass. | 459.5766 |
|---|
| SMILES | [H][C@@](C)(OCc1ccccc1)[C@]1([H])C[C@]23C=C[C@]1(OC)[C@@]1([H])Oc4c5c(C[C@@]2([H])N(C)CCC315)ccc4O |r,c:16,TLB:23:24:14:29.31.32,1:11:33.20:16.15,30:29:24.25.26:14,THB:13:14:24.25.26:29.31.32,15:14:24.25.26:29.31.32| |
|---|
| Structure | 
|
|---|
Search and Browse
