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TargetDelta-type opioid receptor
LigandBDBM50369823
Substrate/Competitorn/a
Meas. Tech.ChEMBL_145471 (CHEMBL751258)
Ki 78±n/a nM
Citation Coop, ANorton, CLBerzetei-Gurske, IBurnside, JToll, LHusbands, SMLewis, JW Structural determinants of opioid activity in the orvinols and related structures: ethers of orvinol and isoorvinol. J Med Chem43:1852-7 (2000) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Delta-type opioid receptor
Name:Delta-type opioid receptor
Synonyms:D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40382.98
Organism:Homo sapiens (Human)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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  Blast E-value cutoff:
BDBM50369823
n/a
NameBDBM50369823
Synonyms:CHEMBL1169582
TypeSmall organic molecule
Emp. Form.C23H29NO4
Mol. Mass.383.4807
SMILESCO[C@@H](C)[C@@H]1CC23C=C[C@]1(OC)[C@H]1Oc4c5c(CC2N(C)CCC315)ccc4O |r,c:7,TLB:14:15:6:19.21.22,2:4:23.12:8.7,22:23:5.4:8.7,20:19:15.16.17:6,THB:15:23:5.4:8.7,5:6:15.16.17:19.21.22,7:6:15.16.17:19.21.22,13:12:5.4:8.7|
Structure
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