| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50369820 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_147233 (CHEMBL754921) |
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| EC50 | 559±n/a nM |
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| Citation |  Coop, A; Norton, CL; Berzetei-Gurske, I; Burnside, J; Toll, L; Husbands, SM; Lewis, JW Structural determinants of opioid activity in the orvinols and related structures: ethers of orvinol and isoorvinol. J Med Chem43:1852-7 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM50369820 |
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| n/a |
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| Name | BDBM50369820 |
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| Synonyms: | CHEMBL1169584 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H31NO4 |
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| Mol. Mass. | 397.5072 |
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| SMILES | CCO[C@@H](C)[C@@H]1CC23C=C[C@]1(OC)[C@H]1Oc4c5c(CC2N(C)CCC315)ccc4O |r,c:8,TLB:15:16:7:20.22.23,3:5:24.13:9.8,23:24:6.5:9.8,21:20:16.17.18:7,THB:16:24:6.5:9.8,6:7:16.17.18:20.22.23,8:7:16.17.18:20.22.23,14:13:6.5:9.8| |
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| Structure | 
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