| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50099622 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_86747 (CHEMBL694088) |
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| Ki | 0.4±n/a nM |
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| Citation |  De Esch, IJ; Mills, JE; Perkins, TD; Romeo, G; Hoffmann, M; Wieland, K; Leurs, R; Menge, WM; Nederkoorn, PH; Dean, PM; Timmerman, H Development of a pharmacophore model for histamine H3 receptor antagonists, using the newly developed molecular modeling program SLATE. J Med Chem44:1666-74 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50099622 |
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| n/a |
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| Name | BDBM50099622 |
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| Synonyms: | 1-Cyclohexylmethyl-3-[2-(1H-imidazol-4-yl)-cyclopropyl]-allyl-ammonium |
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| Type | Small organic molecule |
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| Emp. Form. | C16H26N3 |
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| Mol. Mass. | 260.3972 |
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| SMILES | [NH3+]C(CC1CCCCC1)C=CC1CC1c1cnc[nH]1 |w:9.9| |
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| Structure | 
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